11 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... disease: symptomatic treatment ... Oral/IV Glucocorticoids ... SinaiBmoreIMRes #DRESS #Syndrome ... #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Differential Diagnosis ... Beckwith Wiedemann syndrome ... IGF-1 equivocal: Oral ... Endocrinology #Treatment ... #Pathophysiology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... 50 in GCA, but normal ... Treatment of GCA ... Symptoms #Diagnosis #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management ... #neurology #differential
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Metabolic alkalosis • Normal ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... diagnosis #nephrology #management ... #pathophysiology