4 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... blood cells appear normal ... diagnosis #hematology #oncology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
which is a rare disorder ... cell lymphoma Pathophysiology ... and the systemic symptoms ... phosphatase - Normal ... TAFRO #diagnosis #management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
are usually near-normal ... hemoproliferative disorder ... transformation into MDS or AML ... • Treatment algorithms ... hematology #diagnosis #management