10 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Dabigatran ... #NOAC #DOAC #Pharmacology ... management #Direct #Oral
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... Bridging #Dosing #Oral ... #Apixaban #Rivaroxaban ... #Hematology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin, Apixaban ... - Resume #Oral ... Anticoagulant #DOAC ... #Pharmacology #
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Hepatic, 0% Renal Apixaban ... Hepatic, 35% Renal #DOAC ... #Pharmacology # ... Clearance #oral
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... Xa inhibitors - Apixaban ... ) inhibitors - Dabigatran ... anticoagulation #pharmacology ... #medications #doac
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Antidotes: • Apixaban ... modified factor Xa • Dabigatran ... #Oral #anticoagulant ... #hematology #management ... #pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Rivaroxaban and apixaban ... Dabigatran has moderate ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... per treatment table ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... Management #Treatment #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Fondaparinux, and Novel Oral ... subcutaneous) and oral ... fondaparinux) or a new oral ... a traditional oral ... #Dabigatran #Apixaban
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... concentrations of dabigatran ... , rixaroxaban, apixaban ... thrombin time #doac ... #hematology #laboratory