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diagnosis hematology neurology oncology signs syndrome classification erythematosus lupus sle syndromes systemic vasculitis agglutinin algorithm als amyotrophic ana anemia antinuclear
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... microscopy and serial ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... younger pts) Differential ... Donath-Landsteiner (IgG) antibodies ... hemolytic #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
SLE-Related Auto-Antibodies ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytes • Median ... chemotherapy for low-risk disease ... 3) Monoclonal antibodies ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... pylori test (GI symptoms ... anti-phospholipid antibodies ... bypass), LFT (liver disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Medium and large ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
+ MPO-ANCA MEDIUM ... Presentation - Systemic Symptoms ... aortic aneurysm • Medium ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... EGPA) • Auto-antibodies ... or serologies + symptoms ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... Diagnosis: • Focused medical ... AVNRT Red Flag Symptoms ... /Afib/WPW) • Loss ... Palpitations #Cardiology #Differential
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