12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... microscopy and serial ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
involvement 3% SLE-Related ... Auto-Antibodies ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytes • Median ... Constitutional symptoms ... 3) Monoclonal antibodies ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... anti-phospholipid antibodies ... Causes #Workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large ... Behcet disease) Differential ... Oral aphthae : SLE ... Syndrome #diagnosis #management ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
+ MPO-ANCA MEDIUM ... Presentation - Systemic Symptoms ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... or serologies + symptoms ... blood retum in serial ... Renal #Syndromes #differential ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Involves large and medium ... very remarkable w/differential ... them, but urgent rheumatology ... Temporal #Signs #Symptoms ... #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Bilateral signs and/or symptoms ... Disorders: - SLE ... Antiamphiphysin antibodies ... Myelitis #diagnosis #management ... #neurology #differential