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differential nephrology causes algorithm classification defects epithelial hypokalemia hypomagnesemia inherited kidney magnesium management metabolicalkalosis pathophysiology syndrome tubule workup
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
- Differential Diagnosis ... Chloridorrhea Renal ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
tubular dysfunction ... syndromes - Gitelman ... #Low #Magnesium ... #Table #Classification ... Causes #Workup #hypomg
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... tubular acidosis ... #Diagnosis #Differential ... #Table
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... alkalosis • Normal or low ... • Hypokalemia (renal ... tubular acidosis ... #Syndrome #diagnosis
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