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nephrology differential algorithm causes hypokalemia metabolic alkalosis chloride defects epithelial inherited management metabolicalkalosis pathophysiology pediatrics potassium stones syndrome tubule urinary
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Cells Renal ... ascending limb Gitelman ... tubular acidosis ... #Nephrology #Diagnosis ... #Differential #Table
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
- Differential Diagnosis ... Chloridorrhea Renal ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's ... MetabolicAlkalosis #NonGap
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... Bartter syndrome, Gitelman ... tubular acidosis ... tubular acidosis ... #differential #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... alkalosis • Normal or low ... • Hypokalemia (renal ... tubular acidosis ... #Syndrome #diagnosis
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... suggests extra-renal ... Bartter syndrome, Gitelman ... - Metabolic acidosis ... #Hypokalemia #diagnosis
Metabolic Causes of Kidney Stones in Children • Calcium Oxalate: Primary Hyperoxaluria type 1-3, Secondary Hyperoxaluria
Metabolic Causes of Kidney ... Tubular Acidosis ... Syndrome type 1-4, Lowe ... (Oculo-Cerebro-Renal ... #differential #diagnosis
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