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nephrology differential algorithm causes hypokalemia alkalosis aniongap chloride management pathophysiology syndrome urinary urine
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Losses: • Normal Acid-Base ... Metabolic acidosis ... Bartter syndrome, Gitelman ... Algorithm #causes #potassium ... #low #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... Bartter syndrome, Gitelman ... gap metabolic acidosis ... of sodium and potassium ... #differential #diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Metabolic Acidosis ... Renal acidosis ... Potassium-sparing ... #NonGap #Metabolic ... #diagnosis #causes
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal or low ... • Hypokalemia (renal ... potassium wasting ... tubular acidosis ... #Syndrome #diagnosis
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... Bartter syndrome, Gitelman ... acidosis: Proximal ... #Hypokalemia #diagnosis ... #nephrology #low
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
: Differential Diagnosis ... chronic respiratory acidosis ... tubule diuretic ... furosemide-like lesion) • Gitelman ... other • Severe potassium
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