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adultonset aosd infections syndrome activation adult antinxp2 antinxp2dm cardiomyopathy dermatology dermatomyositis differential fungal hematology hemophagocytic hlh idsa immune infectiousdiseases inflammatory
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... #Disease #diagnosis ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... #Disease #AOSD ... #rheumatology #diagnosis ... #management #treatment
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... : NSAIDS Treatment ... #diagnosis #rheumatology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... +, Adult-onset Still ... disease, Infection ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Valvular heart disease ... e.g., <50%), ESC guidelines ... #management #cardiology ... #treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fever, cough, chills ... pulmonary symptoms • Rheumatologic ... Cough, fever, chills ... extrapulmonary disease ... #Management #Infections
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... pericarditis, peritoneal disease ... Fever, chills, lack ... meningitis • Guidelines ... #Management
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Infection and Disease ... and molecular diagnostic ... Adolescent ARV Guidelines ... #management #opportunistic ... #infections #HIVAIDS
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... had more severe disease ... positive patients Treatment ... Dermatomyositis #diagnosis ... #management #rheumatology
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