11 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Wilsons, Pregnancy - AFLP ... Ducts - PBC ... Algorithm #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... function may be abnormal ... Chronic viral hepatitis ... #differential # ... diagnosis #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... disease US — Normal ... Bile Ducts • PSC ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... • Near normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
• ALT & AST normal ... obstruction • ALP ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... RBC Mass / Decreased ... Abdominal Ultrasound ... Erythrocytosis #Differential ... Algorithm #Causes #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... diagnosis #icp #HELLP #AFLP
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... body mass index; FBC ... mellitus; USS, ultrasound ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
line therapy if ALP ... 1.5x ULN and/or abnormal ... complex: Artificial tears ... survey disease #PBC ... Management #Treatment #hepatology