5 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... initiation • Differential ... 500 mg QD until normal ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... cell types are abnormal ... blood count with differential ... progression to AML ... #diagnosis #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... presence of metabolic syndrome ... mellitus; USS, ultrasound ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Elevation of ALP • Near ... normal AST/ALT ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
WBCs are usually near-normal ... transformation into MDS or AML ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology