9 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... less than 200 cells ... should be based on clinical ... more than 200 cells ... Suspect in movement disorders
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... invades mononuclear cells ... in the CNS ○ ... Infected cells - ... • Depressive symptoms
Endophthalmitis: Infection within the eye. This most commonly occurs via introduction of microbes from the outside
(e.g.
Endophthalmitis: ... the eye. ... of inflammatory cells ... in front of the iris ... #Chemosis #Photo
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
increase in CD4+ cells ... initiation Clinical ... pleural effusions, CNS ... Other Pathogens Associated ... weeks for most OI
Hypopyon: A white layer of inflammatory cells which settles along the bottom of the anterior chamber
of inflammatory cells ... in front of the iris ... , which is an infection ... within the eye ... Ophthalmology #Photo
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Agglutinin Syndrome (CAS ... , autoimmune disorder ... Clinical Presentation ... sensitize red blood cells
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... that results in CNS ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... Pleocytosis > 100 cells
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Arthralgias • Eye ... Multinucleated giant cells ... • Progressive symptoms ... VASCULITIS: ANCA Associated ... chorioretinitis, CNS
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
overgrowth of cells ... syndrome, ANCA-associated ... fast bacterial infection ... and the systemic symptoms ... mature plasma cells