12 results
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... increase in CD4+ cells ... Confusion, visual symptoms ... with severe symptoms ... weeks for most OI
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... detachment • Red Eye ... ophthalmology #diagnosis ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
a dysregulated immune ... vascular endothelial cells ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... tears oint + TAPE eye ... within 4m #Bells
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
IRIS might ... less than 200 cells ... required until immune ... more than 200 cells ... patients with IRIS
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
cell-mediated immune ... various inflammatory cells ... - Formation of immune ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... Physical Exam/Signs ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Microglial cells ... are the immune ... cells of the nervous ... fasciculations Common Symptoms ... between nerve cells
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
within prostate cells ... Inflammation & immune ... immunocompetent cells ... Pathophysiology #Urology #Signs ... #Symptoms #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... Multinucleated giant cells ... • Progressive symptoms