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diagnosis hematology differential leukemia syndrome inflammatory lymphocytic mds myelodysplasia myelodysplastic reconstitution rheumatology sarcoidosis signs vasculitis workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... smear: Blasts APML ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... rendering the immune ... with no early symptoms ... #Chronic #Lymphocytic ... diagnosis #workup #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Syndrome in APML ... Diagnosis: >3 symptoms ... #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Significance (IDUS) • Immune ... progression to AML ... diagnosis #hematology #oncology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... and increased B-cell ... activity → local immune ... tissue: Epithelioid cells ... Sarcoidosis #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... CRP GCA (Giant Cell ... • Progressive symptoms ... Eosinophilia, asthma, chronic
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