13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... • IRIS might ... required until immune ... #Infections #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
increase in CD4+ cells ... pleural effusions, CNS ... Leishmaniasis Differential ... weeks for most OI ... #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... Leukemia #Hematology #Oncology ... #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
: >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management ... #hematology #oncology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... affecting the Brain, Eye ... nervous system (CNS ... noninflammatory #differential ... #diagnosis
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Inflammatory Syndrome (IRIS ... • Caused by immune ... or abruptly • CN ... #Tuberculosis #diagnosis ... #differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... weeks without infection ... phenomenon CLL Diagnosis ... #workup #oncology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... Arthralgias • Eye ... • Progressive symptoms ... chorioretinitis, CNS
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... Bilateral signs and/or symptoms ... #management #neurology ... #differential