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hematology leukemia cll differential syndrome classification differentiation hemeonc hodgkins immune inflammatory lymphoma mds myelodysplasia myelodysplastic reconstitution rheumatology syndromes vasculitis workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... , smudge cells are ... Complications: 1) Infection ... #oncology #hematology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... weeks without infection ... #diagnosis #workup ... #oncology #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
increase in CD4+ cells ... leukoencephalopathy (PML ... with severe symptoms ... weeks for most OI ... #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... : >3 symptoms, or ... : Infection (sepsis ... #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... ingestion • B symptoms ... lymph node biopsy (diagnostic ... classification #hematology #oncology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... • Parvovirus infection ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... • Progressive symptoms ... elevated protein, lymphocytic ... Eosinophilia, asthma, chronic
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