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diagnosis differential syndrome amyotrophic hemeonc hemophagocytic hlh inflammatory lateral leukostasis lymphohistiocytosis lysis neurology reconstitution rheumatology sarcoidosis sclerosis tls tumor vasculitis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... #diagnosis #management ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... increase in CD4+ cells ... such as double ... weeks for most OI ... Differential #Diagnosis #Management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... are the immune ... of UMN and LMN signs ... fasciculations Common Symptoms ... neurology #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... aneurysms can also
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... activity → local immune ... mediators such as ... #Signs #Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Presentation • Common Signs ... and Symptoms: ... Pathophysiology ... #Hematology #HemeOnc
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