11 results
hematology oncology differential leukemia vasculitis behcet classification cll differentiation disease hemeonc hemophagocytic hlh immune inflammatory leukostasis lymphocytic lymphohistiocytosis lysis mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... weeks for most OI ... #Inflammatory #Syndrome ... #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Recurrent and chronic ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... • Richter’s Syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis of tumor cells ... #TLS #diagnosis ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... tissue: Epithelioid cells ... at the time of diagnosis ... #Management #Signs
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... transformation to AML ... Marrow Failure • Chronic ... progression to AML ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... Presentation - Systemic Symptoms ... purpura: strong sign ... Eye -> retinopathy ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... #Rheumatology
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