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diagnosis differential hematology vasculitis chronic classification cll hemeonc hemophagocytic hlh immune inflammatory leukemia lymphocytic lymphohistiocytosis myelitis neurology oncology polychondritis reconstitution
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: Inflammatory eye ... Genital ulcers • Eye ... pathergy test (this is ... #management #signs ... #symptoms #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... What Is IRIS ... increase in CD4+ cells ... weeks for most OI ... Differential #Diagnosis #Management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Skin: - CLL cells ... smear: Smudge cells ... or basket cells
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... purpura: strong sign ... Eye -> retinopathy ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Arthralgias • Eye ... purpura: Strong sign ... Multinucleated giant cells ... vasculitis • Behcet ... Differential #Diagnosis #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Pleocytosis > 100 cells ... disease - Sjogren ... Myelitis #diagnosis #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
overgrowth of cells ... and the systemic symptoms ... mature plasma cells ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... vessels (aorta) • Eyes ... Sarcoidosis • Behcet ... Polychondritis #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Autoimmune diseases ... Presentation • Common Signs ... and Symptoms: ... function of NK cells ... and CD8+ T cells
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