12 results
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement of the eye ... which is described as ... that occurs with eye ... of ectopia lentis ... with Marfan’s syndrome
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement of the eye ... which is described as ... that occurs with eye ... of ectopia lentis ... with Marfan’s syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... Lysis of tumor cells ... #management #hematology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... cells -> Mutagenic ... detachment • Red Eye ... Retinoblastoma #pathophysiology ... #symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... such as double ... weeks for most OI ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
: Inflammatory eye ... Medium and large also ... Genital ulcers • Eye ... #diagnosis #management ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... EMG: LMN Signs in ... neurology #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... mediators such as ... #Signs #Symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... Diagnosis: >3 symptoms ... APML #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Arthralgias • Eye ... purpura: Strong sign ... • Progressive symptoms ... aneurysms can also