10 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... /purpura with fever ... /purpura with fever ... #Diagnosis #Dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... integrity: - Trauma ... Red Flags: • Fever ... cryoglobulins • Skin ... #dermatology #physicalexam
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... - Diagnostic Algorithm ... vascular integrity (trauma ... #Dermatology #Rash ... #Petechiae #Purpura
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... erythroderma, petechiae ... instability - New-onset fever ... sulfa-drug - Skin
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... redness of the skin ... usually to TEN in adults ... Nikolsky sign may ... #Diagnosis #Dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... Complications: MAS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... arthritis (sJIA) • Adult-onset ... manifestation of MAS ... mucosal bleeding (Petechial ... Plasma exchange #MAS
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... • Leukocytosis Diagnosis ... maculopapular skin ... mL Gf consider MAS ... anti-lL6R, anti-ILI #Adult
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... Headaches • Pale skin ... recurrent infections/fevers ... bleeding, and petechiae ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... Headaches, bone pain, fever ... Significant ↓ PLT: Petechiae ... CLL -> Invade Skin ... #Oncology #Diagnosis