29 results
rheumatology treatment differential syndrome dermatology joint signs symptoms workup approach causes erythematosus hemophagocytic lupus lymphohistiocytosis product reactions sle stills summary
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(sJIA) • Adult-onset ... • Fever is the main ... clinical manifestation ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Fever, Arthralgia/arthritis ... Complications: MAS ... #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Clinical Exam: ... hot, swollen, pain ... osteomyelitis, trauma ... necrosis, Lyme disease ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... Previous joint trauma ... #MSK #rheumatology ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... also observed in adults ... #management #treatment ... #hematology
Campylobacter Clinical • Fever • Abdominal pain • Diarrhea (bloody stools) • Vomiting
Campylobacter Clinical ... • Abdominal pain ... • Diarrhea (bloody ... • Reactive arthritis ... Campylobacter #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... common in Asia • HLA-B51 ... association • M > F Clinical ... Nonsurgical abdominal pain ... #management #signs
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... Noninflammatory • Trauma ... • Adult onset ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology #
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