19 results
rheumatology arthritis syndrome treatment differential workup approach dermatology hemophagocytic lymphohistiocytosis summary activation adultonset alkaline alp band behcet calcium classification cppd
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... arthritis (sJIA) • Adult-onset ... • Fever is the main ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... neuropathy so trauma ... #Joint #Pain #MSK ... #rheumatology #
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... Complications: MAS ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... also observed in adults ... #management #treatment ... #hematology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... trauma (e.g., meniscal ... #Pain #MSK #rheumatology ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... Noninflammatory • Trauma ... arthritis • Adult ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Clinical Features ... • A clinical diagnosis ... osteoarticular and skin disease ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Adult form: Less ... Low ALP in adult ... Malnutrition • Wilson's disease ... (muscle/joint)
Iliotibial Band Friction Syndrome - MSK Radiology Imaging Findings: • The iliotibial band (ITB) is thickened with
Friction Syndrome - MSK ... anterolateral knee pain ... Findings of chronic disease ... • Direct trauma ... #msk #clinical
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