20 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #eosinophils #diagnosis ... #management #algorithm
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... Complications: MAS ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... Treatment: admission ... #Management #Summary
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... also observed in adults ... #management #treatment
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Diabetes - Screening, Diagnosis ... and Management ... Algorithm Lifestyle ... ≤ 7.0 % - Most adults ... Endocrinopathies (Cushing Syndrome
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis ... #management #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
presents in young adults ... Presentation - Young adults ... • Or brainstem syndromes ... #management #neurology ... #treatment #MS
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
fractures in young adults ... • Diagnosis: ... H/O antecedent trauma ... #Emergencies #diagnosis ... #management #treatment