30 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Syndrome (MAS) ... arthritis (sJIA) • Adult-onset ... #Syndrome #Diagnosis ... #Management #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Differential Diaqnoses ... Complications: MAS ... #diagnosis #management
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
(MS), Epidural ... Transverse Myelitis, Trauma ... heavy metals), Critical ... #differential #diagnosis ... #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... -> Trauma, disc ... #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
often in older adults ... (Wallenberg's syndrome ... Syndrome usually ... #differential #diagnosis ... #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... #diagnosis #management
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... common type in adults ... include a: • Neurologic ... II ○ Susac’s syndrome ... ○ MS, CVA •
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
and less common diseases ... important, as early diagnosis ... MRI lesions and clinical ... consistent with MS ... #neurology #noninflammatory
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... necrosis, Lyme disease ... #Management #Summary