10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... hepatitis • Pulmonary ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... arthritis (sJIA) • Adult-onset ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... also observed in adults ... Diagnosis via genetic ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... necrosis, Lyme disease ... #Management #Summary
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... common in Asia • HLA-B51 ... association • M > F Clinical ... Behcet syndrome (Clinical ... #management #signs
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... number of sites of disease ... hematology #oncology #management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... vori Infectious Diseases ... #fungal #infectiousdiseases
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Trauma (implantation ... incubation 4 major clinical ... Refractory FUO, Sino-pulmonary ... Fusarium #Infections #infectiousdiseases ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... extrapulmonary disease ... fungal stain of clinical ... ) #Mycoses #InfectiousDiseases ... #Management #Infections