21 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... diseases: SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... : • Infectious ... hepatitis • Pulmonary ... #management #treatment
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
- OnePager Summary ... syndrome etc), Trauma ... Cardiac Tamponade, Pulmonary ... Obstruction (HOCM, critical ... #diagnosis #differential
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
host response to infection ... embolism or severe pulmonary ... commonly due to trauma ... Classification #types #diagnosis ... #management #criticalcare
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
host response to infection ... Cold and Dry) • Pulmonary ... commonly due to trauma ... Classification #Types #diagnosis ... #management #cold
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... washout • Healthy Adults ... #Management #Summary
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... Inflammatory: infectious ... bleeding out (trauma ... Classification #diagnosis ... #management #Overview
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... Inflammatory: infectious ... bleeding out (trauma ... Classification #diagnosis ... #management #Overview
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... also observed in adults ... can mimic common infections ... #management #treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... characteristic features Clinical ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis ... #Management #Treatment