14 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Fever, Arthralgia/arthritis ... #Disease #diagnosis ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... #Disease #AOSD ... #rheumatology #diagnosis ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary ... Clinical Exam: ... osteomyelitis, trauma ... necrosis, Lyme disease ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(sJIA) • Adult-onset ... Still disease ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... #onset #Stills ... diagnosis #rheumatology ... #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... association • M > F Clinical ... skin injury) • Neurologic ... Behcet syndrome (Clinical ... #management #signs
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... Noninflammatory • Trauma ... • Adult onset ... Still's • Ankylosing
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... presents in young adults ... Presentation - Young adults ... stimulation Clinical ... #management #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... , adult-onset Still ... lymphoproliferative syndrome Clinical ... Erythematosus #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : SLE+++, Adult-onset ... Still disease, ... #management #treatment