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management rheumatology hemophagocytic lymphohistiocytosis dermatology differential oncology syndrome workup activation anesthesia anesthesiology arteritis arthritis behcet cardiac checklist chronic classification cll
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... also observed in adults ... : HLH signs and ... symptoms can mimic ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... Drugs, Unknown cause ... Treatment: •
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... (often termed MAS-HLH ... Clinical Presentation ... • Common Signs ... and Symptoms:
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... • Diagnostic ... thoracotomy is a better treatment ... • Fluid bolus (Adult ... examination and vital signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... Hodgkin Lymphoma Treatment ... classification #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... association • M > F Clinical ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... systemic sx + signs ... Treatment of GCA ... #Symptoms #Diagnosis
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism Overview Clinical ... ↑ AST/ALT • Treatment ... hyperthyroidism #causes ... endocrinology #signs ... #symptoms #thyroid
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