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management hemophagocytic lymphohistiocytosis rheumatology anesthesia anesthesiology checklist oncology symptoms syndrome activation arteritis behcet cardiac chronic classification cll differential disease gammopathy
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... also observed in adults ... : HLH signs and ... • Bicytopenia Treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... diseases: SLE+++, Adult-onset ... Drugs, Unknown cause ... Treatment: •
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... hyperinflammatory syndrome caused ... (often termed MAS-HLH ... • Common Signs ... #Management #Hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... thoracotomy is a better treatment ... • Fluid bolus (Adult ... examination and vital signs ... #Management #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... hyperthermia crisis (late sign ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Epidemiology: • Young adults ... common in Asia • HLA-B51 ... association • M > F Clinical ... Arthritis, AS Treatment ... #management #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... systemic sx + signs ... Treatment of GCA ... GCA #Temporal #Signs
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