15 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... in adult population ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... ) Pathophysiology ... headache, malaise) → Acute ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis
Acute limb ischemia (ALI)

Rapid decrease in lower limb blood flow due to acute occlusion of peripheral
Acute limb ischemia ... blood flow due to acute ... Critical Limb ischemia ... entrapment, or trauma ... pathophysiology:
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Medullaris Syndrome -> Trauma ... Injury #Syndromes #diagnosis ... #pathophysiology ... #orthopedics #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Rhabdomyolysis: • Trauma ... Dermatomyositis Clinical ... #Differential #Diagnosis ... causes #treatment #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... syndrome, ADEM, Acute ... #management #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... Guillain-Barre Pathophysiology ... Guillain-Barre Clinical ... variants: (1) acute ... management #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute ... Meningococcal), surgery, trauma ... transplantation CLINICAL ... the underlying pathophysiology ... #management #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Recent history of trauma ... malignancy (Especially acute ... organ damage Clinical ... Bleeding (64%) • Renal ... #Coagulation #diagnosis
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
Acquired disease in adults ... • Concomitant acute ... • Liver and renal ... high index of clinical ... screen Treatment (all