10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... Complications: MAS ... #Disease #diagnosis ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
ROM +/- fever, chills ... osteomyelitis, trauma ... necrosis, Lyme disease ... diagnosis Treatment ... 90% sensitive in pediatrics
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... low ferritin, arthritis ... #AdultOnset #Stills ... #Disease #AOSD
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #onset #Stills
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease,
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... rarely occurs in adults ... , Tachycardia, Arthritis ... #rheumatology #pediatrics ... #treatment
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... Noninflammatory • Trauma ... • Adult onset ... Still's • Ankylosing ... #Differential #Diagnosis
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... , reactivation in ... Standard regimen: Adult ... Regimens: • Adult ... 90-120 days • Pediatric
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... Differential Diagnosis ... , adult-onset Still ... Chronic B-cell activation ... Erythematosus #Diagnosis