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rheumatology differential disease dermatology stills activation adultonset aosd calcium causes cppd ddxof deposition erythematosus lupus macrophage naildisorders onset palpable petechiae
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(MAS) Classified ... arthritis (sJIA) • Adult-onset ... manifestation of MAS ... Plasma exchange #MAS ... #Diagnosis #Management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... solid cancers • Systemic ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Algorithm. ... vascular integrity (trauma ... affected (commonly renal ... and pulmonary ... #Diagnosis #Dermatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
endocarditis • Trauma ... discoloration) • Chronic renal ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... mL Gf consider MAS ... #rheumatology # ... management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Nephrogenic DI Hematologic ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... and renal abnormalities ... Vasculitis Differential Diagnosis ... #Differential #Diagnosis ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... Erythematosus #Diagnosis
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
after surgery/trauma ... culture used to diagnose ... polyarticular CPPD • Systemic ... Crowned Dens Syndrome ... #diagnosis #management
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