10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Management Summary Clinical ... ROM +/- fever, chills ... osteomyelitis, trauma ... Treatment: admission ... washout • Healthy Adults
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Meningococcal), surgery, trauma ... transplantation CLINICAL ... and cauda equina TREATMENT ... specific therapy, the clinician ... ventilation is required
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... Still disease,
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... arthritis (sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... Pneumonia (CAP) - Diagnosis ... be initiated in adults ... with clinically ... #Pulmonary #Community
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... Lymphadenitis, pulmonary ... Fever, chills, lack ... albicans • Epstein Barr
Toxocariasis
Pathogen: Toxocara - worldwide distributed helminth 
Transmission: 
 • Dogs and cats are the major source
• Humans acquire ... Adult worms develop ... larva migrans Diagnosis ... • History + clinical ... #microbiology
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Fusarium Infections Acquired ... Trauma (implantation ... incubation 4 major clinical ... Refractory FUO, Sino-pulmonary ... disease: • Optimal treatment
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
suffered no head trauma ... This patient’s clinical ... exam findings and clinical ... judgement skills ... amount of force is required