12 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
failure • Severe pulmonary ... Epidemiologic exposure + clinical ... Leptospirosis #Leptospira #microbiology ... #diagnosis #treatment ... #management
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... osteomyelitis, trauma ... Treatment: admission ... #Management #Summary
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... #management #treatment
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... and Management ... be initiated in adults ... #Management #treatment ... #Pulmonary #Community
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... arthritis (sJIA) • Adult-onset ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
oxoprolinase • Acquired ... disease in adults ... high index of clinical ... Oxoprolinuria #diagnosis ... #management #treatment
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
cardiothoracic surgery, trauma ... thoracotomy is a better treatment ... • Fluid bolus (Adult ... Plan definitive management ... #Management #Workup
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... Diagnosis = clinical ... of the steroid treatment ... Treatment of GCA ... #Management
Toxocariasis
Pathogen: Toxocara - worldwide distributed helminth 
Transmission: 
 • Dogs and cats are the major source
• Humans acquire ... Adult worms develop ... • History + clinical ... #management #infectiousdiseases ... #treatment #microbiology