8 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Differential Diaqnoses ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Syndrome (MAS) ... the secondary or acquired ... Still disease ... manifestation of MAS ... Plasma exchange #MAS
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... Purtilo (XLP) Acquired ... diseases: SLE+++, Adult-onset ... Still disease,
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... Treatment - Mild ... : NSAIDS Treatment ... #onset #Stills
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... Pneumonia (CAP) - Diagnosis ... be initiated in adults ... #Management #treatment ... #Pulmonary #Community
Approach to Tracheostomy Emergencies - OnePager Summary
COMPONENTS OF A TRACHEOSTOMY TUBE:
 • Obturator - inserted into
available - If still ... , from suction trauma ... hemorrhage will be required ... #Emergencies #diagnosis ... differential #management #pulmonary
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... Generalized: Chills ... Cerebral > Splenic, Pulmonary ... occlusion that may ... hematuria, + RF Treatment
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
suffered no head trauma ... clinical judgement skills ... arise from blunt trauma ... are diagnosed with ... amount of force is required