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diagnosis rheumatology treatment disease hemophagocytic hlh lymphohistiocytosis mas adult adultonset algorithm antinxp2 antinxp2dm aosd bacilliformis bartonella dermatology dermatomyositis fever macrophage
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Complications: MAS ... #AdultOnset #Stills ... Disease #diagnosis #management ... #treatment #rheumatology
Proposed Treatment Algorithm for MAS / HLH #MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Algorithm for MAS ... / HLH #MAS # ... Lymphohistiocytosis #Management ... Treatment #Algorithm #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... • Adult-onset Still ... manifestation of MAS ... Plasma exchange #MAS ... #Hematology #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... mL Gf consider MAS ... #Adult #onset #Stills ... AOSD #diagnosis #rheumatology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... +, Adult-onset Still ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... fever, malaise, chills ... coinfection, toxo reactivation ... Fever #diagnosis #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... Dermatomyositis: • ILD was ... Dermatomyositis #diagnosis #management ... #rheumatology # ... dermatology
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