18 results
Portal Hypertension Classification by site of vascular obstruction
1) Post-hepatic Post-sinusoidal: Budd-Chiari syndrome
2) Intrahepatic Post-sinusoidal: Veno-occlusive disease
3)
Portal Hypertension Classification ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... or secondary to cirrhosis ... gastroenterology #diagnosis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Failure (ACLF) Clinical ... of underlying liver ... disease, liver ... support, or liver
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... Chronic - ongoing ↑ LFTs ... or symptoms of liver ... disease 6-9 mo ... Drug #induced #Liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... Infiltrative • Cirrhosis ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... transaminitis #LFTs
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Veno-occlusive disease
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... the pattern of liver ... #LFTs #Abnormal ... #Enzymes #Differential
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
progression to end-stage liver ... indications for liver ... and end-stage liver ... disease management ... remain subject to clinical
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Patients with cirrhosis ... A liver biopsy can ... disease. ... biopsy or MRI. ... algorithm #diagnosis #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... the spleen or liver ... translocation • Types: Classification ... Noncontiguous spread • Clinical ... involvement Differential