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diagnosis causes hepatology algorithm criticalcare hypertension management overview acidosis chemistry comparison elevation gastroenterology hematology hepatitis hepatorenal hodgkins hrs injury interpretation
Portal Hypertension Classification by site of vascular obstruction 1) Post-hepatic Post-sinusoidal: Budd-Chiari syndrome 2) Intrahepatic Post-sinusoidal: Veno-occlusive disease 3)
Classification ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... or secondary to cirrhosis ... gastroenterology #diagnosis #differential
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential ... >10 mmHg - clinically ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Veno-occlusive disease
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... chemistry #diagnosis #differential ... transaminitis #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... Infiltrative • Cirrhosis ... • Others #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Hepatic artery: Shock ... VZV • Trauma: Shock ... hepatitis: < 1 • Cirrhosis ... injury #hepatitis #differential
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... AI, thyroid dz liver ... O2 delivery • MI ... #Classification ... #criticalcare #differential
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... AI, thyroid dz liver ... O2 delivery • MI ... #Classification ... #criticalcare #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... the spleen or liver ... translocation • Types: Classification ... also arise in normal ... involvement Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
glucose by the liver ... presentations and disease ... contribution of liver ... mellitus/DKA - Liver ... gluconeogenesis Liver
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Occurs in advanced liver ... disease: cirrhosis ... hepatitis, or acute liver ... • Definitive: Liver ... • Urgent liver
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