12 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
ulcerations • Skin ... auricular papules Clinical ... onset [33-74%] • Blood ... severity of the disease ... Dermatomyositis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... pulses, bruits, or blood ... oligoclonal bands • MRI ... tract, and often causes ... #Diagnosis #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... - MRI: inflammation ... disease. ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... eruptions, diarrhea, liver ... infections with skin ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... eruptions, diarrhea, liver ... infections with skin ... Transfusions #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... Disease: - Impaired ... #treatment #management ... #hematology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... , hair growth, skin ... tags, skin thickening ... Differential Diagnosis ... • Pituitary MRI
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... Reversible course Differential ... elevated white blood ... the underlying cause ... Syndrome #diagnosis #management