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diagnosis dermatology hematology vulnificus amyloid bullae cellulitis gap globulin infection legs management nejm nonpalpable palpable protein proteingap purpura rash sjogrens
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
skin infection ... sepsis: chronic liver ... disease, iron overload ... #Vulnificus #skin ... #photo
Vibrio vulnificus Infection- At the time of presentation, hemorrhagic bullae measuring 3.5 by 4.5 cm had
vulnificus can cause ... skin infections ... including chronic liver ... disease and cancer ... #clinical #photo
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... deficiency • Liver ... Dermal Vessels: - Amyloidosis ... #rheumatology #
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... the extent of disease ... Clinical Manifestations ... waxy or thickened skin ... enlargement • MRI
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... PE, Pulmonary amyloidosis ... vasculitis: 10%-16% Liver ... Sjogrens #Syndrome #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
macroglobulinemia • Amyloidosis ... gammopathy, and skin ... (light chain) amyloidosis ... Sarcoidosis) • Liver ... Gap #ProteinGap #differential
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