12 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient (SAAG ... ) SAAG ≥ 1.1: ... syndrome, Massive liver ... #gradient #hepatology ... #differential #
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Alcoholic hepatitis ... - Acute fatty ... liver of pregnancy ... #hepatology #SAAG
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
- Alcoholic hepatitis ... - Massive liver ... disease - Acute fatty ... liver of pregnancy ... #Diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... develops (DIC, ascites ... #Liver #Pregnancy ... #hepatology #obstetrics
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... liverprof #Diagnosis #Hepatology ... #SAAG #Ascites ... Interpretation #Differential
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... (SAAG>I.I), esophageal ... sarcoidosis) • Liver ... liver of pregnancy ... Diagnosis #causes #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... cirrhosis or chronic hepatitis ... #Differential # ... Diagnosis #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty ... Liver • Cysts ... #Hepatomegaly #Differential ... Algorithm #Causes #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... - Nonalcoholic fatty ... liver disease ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... Liver of Pregnancy ... features: Liver ... Disease #Pregnancy #hepatology