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diagnosis liver algorithm hepatitis phosphatase pregnancy transaminitis abnormal biliary causes chemistry cholangitis cirrhosis comparison elevation enzymes fatty hellp hepatocellular hyophosphatasia
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Diagnosis Algorithm ALP ... - Increased ALP ... Surgical consult ALP ... #Phosphatase #ALP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
compared with alkaline ... disproportionate increase in alkaline ... HELLP, Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... in 1923 Low ALP ... synthesized in: liver ... Malnutrition • Wilson's disease ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... iMedEducation #AFLP ... Pregnancy #hepatology ... #obstetrics #obgyn
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... of Pregnancy (AFLP ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
PBC Labs: • Alkaline ... but elevated as disease ... obstruction • ALP ... bile ducts Differential ... diagnosis #workup #hepatology
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