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diagnosis aflp management obstetrics pregnancy classification coagulation comparison disease disseminated elevation hellp hematology hepatitis hypertension icp intravascular lactate lactic obgyn
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... develops (DIC, ... #Liver #Pregnancy
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... and hemorrhage Acute ... Fatty Liver of ... features: Liver
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... • Cirrhosis/acute ... sarcoidosis) • Liver ... liver of pregnancy ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... glucose by the liver ... contribution of liver ... mellitus/DKA - Liver ... gluconeogenesis Liver
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... organ damage Clinical ... dysfunction (16%) • Shock ... • Severe Liver ... Treat primary cause
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