10 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... infiltration) Differential ... #Fatty #Liver # ... Pregnancy #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Wilsons, Pregnancy - AFLP ... Burak @kwburak #LFTs ... #hepatology #LiverFunctionTests
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
(AFLP) • Onset ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis ... #LFTs #RValue #
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
ALP, alkaline phosphatase ... non-alcoholic fatty ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... metastasis • Fatty ... #hepatology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... which mobilizes fatty ... In both SK and AK ... #diagnosis #differential ... #algorithm #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... renal failure Clinical ... anterior/posterior MSK ... (pain/abnormal LFT ... #Management #Signs