17 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... tests in pregnancy ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... (Drug-induced liver ... Hepatopathy (shock liver ... LouLectures #Liver ... Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Alcoholic hepatitis ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... AIH, Wilsons, Pregnancy ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... of Pregnancy (AFLP ... features: Liver ... #differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... hepatocytes → Liver ... #Fatty #Liver # ... Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Interpretation of LFTs ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... melanoma, myeloma • Pregnancy ... #injury #hepatitis ... #differential # ... diagnosis #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... Artery: Shock Liver ... Toxic: Medication, Pregnancy ... Acute #algorithm #hepatology