10 results
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... Renal: metabolic acidosis ... AI, thyroid dz liver ... Classification #diagnosis #management ... #criticalcare #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... of lactate as a clinical ... a multitude of clinical ... the appropriate clinical ... #Elevation #Differential
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... cycle found in the liver ... presentation - Clinical ... Toxicology #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... infiltration) Differential ... Maternal Support - Critical ... obgyn #diagnosis #management ... #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Framework and Clinical ... seen • Lactic acidosis ... GFR • Acute liver ... beriberi #nutrition #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... GrepMed Handbook Clinical ... malignancy Pathophysiology ... GH stimulates liver ... Differential Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... dysfunction (16%) • Shock ... DIC • Severe Liver ... causes #treatment #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... Reversible course Differential ... Syndrome #diagnosis #management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
tubule (DCT) Clinical ... ratio 0.5%) Differential ... Renal tubular acidosis ... diagnosis #nephrology #management ... #pathophysiology