39 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... months without treatment ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... obstruction, HELLP Syndrome ... #Injury #Differential ... #algorithm #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... > 3 mg/dL) or acute ... #HepatitisB #HepBV ... #Indications #management ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #differential #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... (eg Viral) Management ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... and hepatorenal syndrome ... • Cirrhosis/acute ... hepatitis • Infiltrative
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... and hemorrhage Acute ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential