10 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... , Mononeuritis multiplex ... #differential #diagnosis ... #neurology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... Summary Clinical ... demineralization) • Renal disease ... if FLC value is also
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Clinical Features ... Decreased / Absent Reflexes ... Diagnosis: • ... #management #treatment ... #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
brainstem and multiple ... Increased Jaw Jerk reflex ... , Clonus, Spasticity ... Lateral #Sclerosis #neurology ... #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... syndromes such as ... Hyperreflexia, Clonus ... stimulation Clinical ... #management #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... depressed deep tendon reflexes ... specific therapy, the clinician ... #management #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
inflammation of multiple ... association • M > F Clinical ... skin injury) • Neurologic ... Medium and large also ... #management #signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... is also observed ... associated with multiple ... #management #treatment
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Spasticity - Reflexes ... suggestive of multiple ... Demyelination: - Multiple ... #management #neurology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
profile, including liver ... (to support a diagnosis ... electrophoresis (to exclude multiple ... ANA and RF (if clinical ... laboratory #workup #diagnosis