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hematology differential leukemia management anemia behcet cll cutaneous dermatologic erythematosus gpa granulomatosis lupus lymphocytic manifestations mds monoclonal myelodysplasia paraproteinemias polyangiitis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... leukocytoclastic vasculitis ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Differential Diagnosis ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anemia Clinical ... Headaches • Pale skin ... • Hypocellular myelodysplastic ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... Pure red cell aplasia ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #Syndromes #diagnosis ... #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... Ischemia, Leukemia, Lymphoma ... Recurrent and chronic ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Alpha & Mu) Skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... with Lupus: • Chronic ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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